Speed T4

Quantitative determination of serum or plasma total circulating T4

Presentation

Advantages

Method: Immunochromatography

Analysis: Quantitative determination of the total circulating serum or plasma T4

Sample: Serum, heparinized plasma

Reading: 15 minutes (including 5 minutes incubation)

Presentation: 6 tests

Storage: 18 months between 2°C and 8°C

Performances: The correlation coefficient R² is 0.91 and 0.95 for the canine and feline samples respectively ⁽¹⁾

Speed T4 ^TM can be used to measure total blood T4 in both dogs and cats.

Simple and fast to implement, Speed T4 ^TM allows the practitioner to extend the screening performed during the senior balance sheets and to carry out regular and accurate follow-up thanks to a quantitative result.

Why use Speed T4^TM?
Hypothyroidism and hyperthyroidism are among the most common endocrine disorders in dogs and cats. ^{(2) (3) (4)} Thyroxine is a hormone synthesized by the thyroid gland. Measurement of total T4 provides useful information for the selection and diagnosis of thyroid diseases.

When to use Speed T4^TM?
Hypothyroidism is the most common endocrine disorder in older dogs. Whereas diagnoses are made on average at the age of 7 years, the so-called "at risk" breeds (Doberman, Pinscher, Golden Retriever, etc.) can present symptoms as early as 2 years of age. ⁽⁴⁾ In cats, hyperthyroidism is most commonly diagnosed between 12 and 13 years of age. Some risk factors increase the likelihood of hyperthyroidism such as wet food or sex (females are more commonly affected)⁽²⁾⁽³⁾

When to use Speed T4^TM?

Hypothyroidism is the most common endocrine disorder in older dogs. Whereas diagnoses are made on average at the age of 7 years, the so-called "at risk" breeds (Doberman, Pinscher, Golden Retriever, etc.) can present symptoms as early as 2 years of age. ⁽⁴⁾

In cats, hyperthyroidism is most commonly diagnosed between 12 and 13 years of age. Some risk factors increase the likelihood of hyperthyroidism such as wet food or sex (females are more commonly affected)⁽²⁾⁽³⁾

Protocol for the use of Speed T4^TM

See study

References
(1) B. Rannou, Evaluation of a new point-of-care immunoassay (Speed T4™) in the measurement of feline and canine total thyroxine, ESVCP Congrés de Nantes, Octobre 2016.

(2) Carney HC, Ward CR, Bailey SJ, Bruyette D, Dennis S, Ferguson D, Hinc A, Rucinsky AR. 2016 AAFP Guidelines for the Management of Feline Hyperthyroidism. J Feline Med Surg. 2016 ;18:400-16
(3) Ettinger SJ, Feldman EC. Textbook of Veterinary Internal Medicine. 7th Edition, 2010. Saunders Elsevier, St Louis, Missouri. ISBN: 978-9996962837 (v.2)
(4) Feldman EC, Nelson RW, Reusch C and Scott-Moncrieff JC. Canine and Feline Endocrinology. 4th Edition, 2015. Saunders Elsevier, St Louis, Missouri. ISBN: 978-1-4557-4456-5.
(5) Graham P.A. et al. Etiopathologic findings of canine hypothyroidism. Vet Clin N Am Small Anim Pract 2007;37: 617-632